Me: 36, Endo, DOR
DH: 39, Low morphology, otherwise healthy
Dec 2005–Dx with ovarian cysts, advised to operate. Took BCP for a year, cysts disappeared!
Dec 2010–Got married ❤
July 2011–decided to start trying for baby. First doc appt. told have huge fibroid in uterus (8cm), advised immediate surgery. Total freakout, in denial for 6 months.
Sept-Nov 2011: try naturally with ovulation trigger (HCG). BFN
Dec 2011: 1st IUI (natural). BFN.
Jan 2012: Laparoscopic myomectomy. Fibroid successful removed, slight blockage indicated in left tube. Advised to hold off ttc for 3 months. Start acupuncture.
April 2012: Move to Bay Area. New RE. Dx with PCOS, endo, IR. Put on metformin 1000mg/ daily, several supplements, asked to walk after each meal, yoga, acupuncture etc. Resume ttc. BFP on first try!! Ecstatic!!
May 2012: 1st u/s shows nothing. HCG plateaus. Suspected ectopic. D&C w/ methotrexate. Devastated
June 2012: frozen labs confirm uterine pregnancy aka regular miscarriage not ectopic. Thank God!
July 2012: Rubella shot, cannot try this month
Aug 2012: BFN
Sept 2012: 2nd natural IUI. Everything looks great but BFFN! Plus, suspected OHSS from HCG shot later revised to possible endo flare-up. Left ovary enlarges and stays enlarged for 2 months. In extreme pain. Emergency surgery advised.
Nov 2012: Left ovary finally starts shrinking.
Dec 2012: Hawaii!! BFN though
Jan 2013: BFN. Start looking for IVF options.
Feb 2013: Anastrozole + BCP + Doxy to try shrink endo. India vacation = family time
March 2013: Pre-IVF workup. Advised surgery for left side hyrdosalpinx. Dx with low AMH (0.48), slightly elevated immunology: blood clotting antibodies + TH1/ cytokines. Rx: baby aspirin, Lovenox at time of transfer and 2 intra-lipid infusions before and after ER.
April 2013: Laparoscopy to clip left tube and remove surface endo. Surgery successful.
May 2013: IVF # 1 Antagonist protocol. 9 follies, 7 eggs retrieved, 5 mature, 3 make it to day 6 blasts. All chromosomally abnormal. FET canceled. Advised donor eggs. Shattered.
June 2013: BFN
July 2013: onwards to exploring new options.
August 2013: Initial consult with Dr Surrey. Travel to CO for OWDU. Results in: AMH: 1.3, FSH: 10.3, E2: 65, LH: 6, Immunology fine, Karotype: normal for both, TSH: 2.3, Genetic panel testing: all ok.
September 2013: Regroup with Dr S to discuss test results. Green signal for starting cycle in October.
9/21: DH and I begin Doxy
Waiting for LH surge.
10/4: Get LH surge! Given go-ahead to begin estrace in 10 days!
10/14: Begin estrace
10/15: Begin daily cetrotide injections
10/18: Period starts. Suppression check: all clear!!!!
10/19: Begin stims
10/31: ER. 11 retrieved (yayy!), only 6 mature (boo!), 3 more mature overnight in lab. Total of 6 fertilized and frozen. We will be banking our embryos and coming back for another cycle.
1/21: ER. 17 retrieved, 15 mature, 12 fertilized (yayy!). 12 + 6 day 1’s (from first cycle) grown till day 5. 9 beautiful blasts. CCS testing reveals 6 normals, 2 no results!!
Feb 2014: Endometrial biopsy reveals missing beta-3 integrin protein. Rx: 2 months of depot lupron.
3/4: Depot Lupron shot 1
4/4: Depot Lupron shot 2
5/3: Begin FET meds
5/23: FET on 1 beautiful hatching 5AA CCS normal blast
6/1: BFP! Beta 1: 351, Beta 2: 892